Историческая ретроспектива знаний о молочной кислоте и роли лактата в метаболизме
Ключевые слова:
молочная кислота, лактат, кислородный долг, порог анаэробного обмена, метаболит, метаболизм
Аннотация
В статье рассматривается история открытия молочной кислоты, эволюция знаний о ней. Делается обзор исследований о роли и месте лактата в метаболизме и спортивной деятельности, в процессе соревновательных и тренировочных воздействий с момента открытия молочной кислоты и до наших дней. В ходе исследования раскрыта эволюция знаний о молочной кислоте, обозначен вектор современных исследований в данной области, современные представления о роли лактата в метаболизме и спортивной деятельности.
Литература
1. Мещерякова, О. В. Митохондриальныйлактат-окисляющий комплекс и его значение для поддержания энергетического гомеостаза клеток (обзор) / О. В. Мещерякова, М. В. Чурова, Н. Н. Немова // Современные проблемы физиологии и биохимии водных организмов. Том I. Экологическая физиология и биохимия водных организмов (сборник научных статей). – Петрозаводск: Карельский научный центр РАН, 2010. – С. 163–171.
2. Молочная кислота: динамика представлений о биологии лактата / С. В. Чепур, Н. Н. Плужников, О. В. Чубарь [и др.] // Успехи современной биологии. – 2021. – Т. 141, № 3. – С. 227–247.
3. A comparison of gas exchange indices used to detect the anaerobic threshold / V. J. Caiozzo, J. A. Davis, J. F. Elus[et al.] // Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. – 1982. – Vol. 53, Iss. 5. – P. 1184–1189.
4. Araki, T. Ueber die Bildung von Milchsäure und Glycose imOrganismusbeiSauerstoffmangel. DritteMittheilung / T. Araki // ZeitschriftfürPhysiologischeChemie. – 1892. – Vol. 16. – P. 453–459.
5. Astrand, I. Aerobic work capacity in men and women with special reference to age / I. Astrand//ActaphysiologicaScandinavica. Supplementum. – 1960. – Vol. 49, Iss. 169. – P. 1–92.
6. Barr, D. P. Studies in the physiology of muscular exercise. III. Development and duration of changes in acid-base equilibrium / D. P. Barr, H. E. Himwich// Journal of Biological Chemistry. – 1923. – Vol. 55, Iss. 3. – P. 539–555.
7. Brooks, G. A. The metabolic systems: anaerobic metabolism (glycolytic and Phosphagen) / G. A. Brooks, L. B. Gladden // Exercise physiology people and ideas. – New York: Springer,2020. – P. 322–360.
8. Brooks, G. A. The science and translation of lactate shuttle theory / G. A. Brooks // Cell metabolism. – 2018. – Vol. 27, Iss. 4. – P. 757–785.
9. Cori, C. F. Changes in hexosephosphate, glycogen, and lactic acid during contraction and recovery of mammalian muscle / C. F. Cori, G. T. Cori // Journal of Biological Chemistry. – 1933. – Vol. 99, Iss. 2. – P. 493–505.
10. Disposal of blood [l-l3C] lactate in humans during rest and exercise / R. S. Mazzeo, G. A. Brooks, D. A. Schoeller[et al.] // Journal of Applied Physiology. – 1986. – Vol. 60, Iss. 1. – P. 232–241.
11. Du Bois-Reymond, E. Bemerkungenüber die Reaction der elektrischenOrgane und der Muskeln /E. Du Bois-Reymond. – Berlin, 1859. – 8 p.
12. Embden, G. Uber die Chemie des Lactacidogens. II / G. Embden, F. Laquer// Hoppe-Seyler'sZeitschrift Fur PhysiologischeChemie. – 1917. – Vol. 98. – P. 181.
13. Endurance training increases gluconeogenesis during rest and exercise in men / B. C. Bergman, M. A. Horning, G. Casazza[et al.] //. American journal of physiology.Endocrinology and metabolism. – 2000. – Vol. 278, Iss. 2. – P. E244–E251.
14. Fletcher, W. M. Lactic acid in amphibian muscle / W. M. Fletcher, F. G. Hopkins // The Journal of physiology. – 1907. – Vol. 35(4). – P. 247–309.
15. Hermansen, L. Muscle glycogen during prolonged severe exercise / L. Hermansen, E. Hultman, B. Saltin// ActaPhysiologicaScandinavica. – 1967. – Vol. 71, Iss. 2–3. – P. 129–139.
16. Hill, A. V. Muscular exercise, lactic acid, and the supply and utilisation of oxygen: Parts I-III / A. V. Hill, C. N. H. Long, H. Lupton // Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character. – 1924. – Vol. 96. – №. 679. – P. 438–475.
17. Hill, A. V.The heat produced in contracture and muscular tone / A. V. Hill // The Journal of Physiology. – 1910. – Vol. 40, Iss. 5. – P. 389–403.
18. Hollmann, W. Historical remarks on the development of the aerobic-anaerobic threshold up to 1966 / W. Hollmann //International journal of sports medicine. – 1985. – Vol. 6, Iss. 3. – P. 109–116.
19. Hollmann, W. The Anaerobic Threshold as a Tool in Medicine / W. Hollmann // Advances in Ergometry. – NewYork: Springer-Verlag, 1991. – P. 1–11.
20. Lactate: Friend or Foe / M. M. Hall, S. Rajasekaran, T. W. Thomsen[et al.] // Advanced Sports Medicine Concepts and Controversies. – 2016. – Vol. 8, Iss.3. – P. 8–15.
21. Margaria, R. The possible mechanisms of contracting and paying the oxygen debt and the role of lactic acid in muscular contraction / R. Margaria, H. T. Edwards, D. B. Dill // The American Journal of Physiology. – 1933. – Vol. 106, Iss. 3. – P. 689–715.
22. Meyerhof, O. Die EnergieumwandlungenimMuskel. III. Kohlenhydrat- und MilchsäureumsatzimFroschmuskel / O. Meyerhof // Pflüger'sArchivfür die gesamtePhysiologie des Menschen und der Tiere. – 1920. – Vol. 185, Iss. 1. – P. 11–32.
23. Müller, E. A. Die PulszahlalsKennzeichenfürStoffaustausch und Ermüdbarkeit des arbeitendenMuskels / E. A. Müller // Arbeitsphysiologie. – 1942. – Vol. 12, Iss. 1. – P. 92–104.
24. Owles, W. H. Alterations in the lactic acid content of the blood as a result of light exercise, and associated changes in the СО2-combining power of the blood and in the alveolar СО2 pressure / W. H. Owles // The Journal of physiology. – 1930. – Vol. 69, Iss. 2. – P. 214–237.
25. San-Millan, I. Assessment of metabolic flexibility by means of measuring blood lactate, fat, and carbohydrate oxidation responses to exercise in professional endurance athletes and less-fit individuals / I. San-Millan, G. A. Brooks // Sports medicine. – 2018. – Vol. 48, Iss.2. – P. 467–479.
26. TGF-β2 is an exercise-induced adipokine that regulates glucose and fatty acid metabolism / H. Takahashi, C. R. R. Alves, K. I. Stanford [et al.] // Nature metabolism. – 2019. – Vol. 1, Iss. 2. – P. 291–303.
27. The anaerobic threshold: 50+ years of controversy / D. C. Poole, H. B. Rossiter, G. A. Brooks [et al.] // The Journal of physiology. – 2021. – Vol. 599, Iss. 3. – P. 737–767.
28. The Chemistry of Life: Eight Lectures on the History of Biochemistry / R. Hill, F. G. Young, M. Dixon [et al.]; edited with an introduction, by Joseph Needham. – Cambridge, England: University Press, 1971. – 213 p.
29. Von Muralt, A. The development of muscle-chemistry, a lesson in neurophysiology/ A. Von Muralt // BiochimicaetBiophysicaActa. – 1950. – Vol. 4. – P. 126–129.
30. Wasserman, K. Detecting the threshold of anaerobic metabolism in cardiac patients during exercise / K. Wasserman, M. B. McIlroy // The American journal of cardiology. – 1964. – Vol. 14, Iss. 6. – P. 844–852.
2. Молочная кислота: динамика представлений о биологии лактата / С. В. Чепур, Н. Н. Плужников, О. В. Чубарь [и др.] // Успехи современной биологии. – 2021. – Т. 141, № 3. – С. 227–247.
3. A comparison of gas exchange indices used to detect the anaerobic threshold / V. J. Caiozzo, J. A. Davis, J. F. Elus[et al.] // Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. – 1982. – Vol. 53, Iss. 5. – P. 1184–1189.
4. Araki, T. Ueber die Bildung von Milchsäure und Glycose imOrganismusbeiSauerstoffmangel. DritteMittheilung / T. Araki // ZeitschriftfürPhysiologischeChemie. – 1892. – Vol. 16. – P. 453–459.
5. Astrand, I. Aerobic work capacity in men and women with special reference to age / I. Astrand//ActaphysiologicaScandinavica. Supplementum. – 1960. – Vol. 49, Iss. 169. – P. 1–92.
6. Barr, D. P. Studies in the physiology of muscular exercise. III. Development and duration of changes in acid-base equilibrium / D. P. Barr, H. E. Himwich// Journal of Biological Chemistry. – 1923. – Vol. 55, Iss. 3. – P. 539–555.
7. Brooks, G. A. The metabolic systems: anaerobic metabolism (glycolytic and Phosphagen) / G. A. Brooks, L. B. Gladden // Exercise physiology people and ideas. – New York: Springer,2020. – P. 322–360.
8. Brooks, G. A. The science and translation of lactate shuttle theory / G. A. Brooks // Cell metabolism. – 2018. – Vol. 27, Iss. 4. – P. 757–785.
9. Cori, C. F. Changes in hexosephosphate, glycogen, and lactic acid during contraction and recovery of mammalian muscle / C. F. Cori, G. T. Cori // Journal of Biological Chemistry. – 1933. – Vol. 99, Iss. 2. – P. 493–505.
10. Disposal of blood [l-l3C] lactate in humans during rest and exercise / R. S. Mazzeo, G. A. Brooks, D. A. Schoeller[et al.] // Journal of Applied Physiology. – 1986. – Vol. 60, Iss. 1. – P. 232–241.
11. Du Bois-Reymond, E. Bemerkungenüber die Reaction der elektrischenOrgane und der Muskeln /E. Du Bois-Reymond. – Berlin, 1859. – 8 p.
12. Embden, G. Uber die Chemie des Lactacidogens. II / G. Embden, F. Laquer// Hoppe-Seyler'sZeitschrift Fur PhysiologischeChemie. – 1917. – Vol. 98. – P. 181.
13. Endurance training increases gluconeogenesis during rest and exercise in men / B. C. Bergman, M. A. Horning, G. Casazza[et al.] //. American journal of physiology.Endocrinology and metabolism. – 2000. – Vol. 278, Iss. 2. – P. E244–E251.
14. Fletcher, W. M. Lactic acid in amphibian muscle / W. M. Fletcher, F. G. Hopkins // The Journal of physiology. – 1907. – Vol. 35(4). – P. 247–309.
15. Hermansen, L. Muscle glycogen during prolonged severe exercise / L. Hermansen, E. Hultman, B. Saltin// ActaPhysiologicaScandinavica. – 1967. – Vol. 71, Iss. 2–3. – P. 129–139.
16. Hill, A. V. Muscular exercise, lactic acid, and the supply and utilisation of oxygen: Parts I-III / A. V. Hill, C. N. H. Long, H. Lupton // Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character. – 1924. – Vol. 96. – №. 679. – P. 438–475.
17. Hill, A. V.The heat produced in contracture and muscular tone / A. V. Hill // The Journal of Physiology. – 1910. – Vol. 40, Iss. 5. – P. 389–403.
18. Hollmann, W. Historical remarks on the development of the aerobic-anaerobic threshold up to 1966 / W. Hollmann //International journal of sports medicine. – 1985. – Vol. 6, Iss. 3. – P. 109–116.
19. Hollmann, W. The Anaerobic Threshold as a Tool in Medicine / W. Hollmann // Advances in Ergometry. – NewYork: Springer-Verlag, 1991. – P. 1–11.
20. Lactate: Friend or Foe / M. M. Hall, S. Rajasekaran, T. W. Thomsen[et al.] // Advanced Sports Medicine Concepts and Controversies. – 2016. – Vol. 8, Iss.3. – P. 8–15.
21. Margaria, R. The possible mechanisms of contracting and paying the oxygen debt and the role of lactic acid in muscular contraction / R. Margaria, H. T. Edwards, D. B. Dill // The American Journal of Physiology. – 1933. – Vol. 106, Iss. 3. – P. 689–715.
22. Meyerhof, O. Die EnergieumwandlungenimMuskel. III. Kohlenhydrat- und MilchsäureumsatzimFroschmuskel / O. Meyerhof // Pflüger'sArchivfür die gesamtePhysiologie des Menschen und der Tiere. – 1920. – Vol. 185, Iss. 1. – P. 11–32.
23. Müller, E. A. Die PulszahlalsKennzeichenfürStoffaustausch und Ermüdbarkeit des arbeitendenMuskels / E. A. Müller // Arbeitsphysiologie. – 1942. – Vol. 12, Iss. 1. – P. 92–104.
24. Owles, W. H. Alterations in the lactic acid content of the blood as a result of light exercise, and associated changes in the СО2-combining power of the blood and in the alveolar СО2 pressure / W. H. Owles // The Journal of physiology. – 1930. – Vol. 69, Iss. 2. – P. 214–237.
25. San-Millan, I. Assessment of metabolic flexibility by means of measuring blood lactate, fat, and carbohydrate oxidation responses to exercise in professional endurance athletes and less-fit individuals / I. San-Millan, G. A. Brooks // Sports medicine. – 2018. – Vol. 48, Iss.2. – P. 467–479.
26. TGF-β2 is an exercise-induced adipokine that regulates glucose and fatty acid metabolism / H. Takahashi, C. R. R. Alves, K. I. Stanford [et al.] // Nature metabolism. – 2019. – Vol. 1, Iss. 2. – P. 291–303.
27. The anaerobic threshold: 50+ years of controversy / D. C. Poole, H. B. Rossiter, G. A. Brooks [et al.] // The Journal of physiology. – 2021. – Vol. 599, Iss. 3. – P. 737–767.
28. The Chemistry of Life: Eight Lectures on the History of Biochemistry / R. Hill, F. G. Young, M. Dixon [et al.]; edited with an introduction, by Joseph Needham. – Cambridge, England: University Press, 1971. – 213 p.
29. Von Muralt, A. The development of muscle-chemistry, a lesson in neurophysiology/ A. Von Muralt // BiochimicaetBiophysicaActa. – 1950. – Vol. 4. – P. 126–129.
30. Wasserman, K. Detecting the threshold of anaerobic metabolism in cardiac patients during exercise / K. Wasserman, M. B. McIlroy // The American journal of cardiology. – 1964. – Vol. 14, Iss. 6. – P. 844–852.
Опубликован
08-11-2024
Как цитировать
Ходанович, А. Н., Филина, И. А., & Никитин, А. В. (2024). Историческая ретроспектива знаний о молочной кислоте и роли лактата в метаболизме. Физическая культура. Спорт. Туризм. Двигательная рекреация, 9(4), 66-73. https://doi.org/10.47475/10.47475/2500-0365-2024-9-4-66-73
Раздел
ТЕОРИЯ И ИСТОРИЯ ФИЗИЧЕСКОЙ КУЛЬТУРЫ, СПОРТА, ТУРИЗМА
Copyright (c) 2024 Андрей Николаевич Ходанович, Ирина Александровна Филина, Алексей Валентинович Никитин
Это произведение доступно по лицензии Creative Commons «Attribution-NonCommercial» («Атрибуция — Некоммерческое использование») 4.0 Всемирная.
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